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KMID : 0370920040210020231
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Yeungnam Univercity Journal of Medicine
2004 Volume.21 No. 2 p.231 ~ p.236
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A Case of congenital Factor VII Deficiency Presented With Subacute Subdural Hematoma
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Kim MK
Shin SJ/Kim KO/Lee KH/Hyun MS/Cho HS
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Abstract
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A congenital factor VII deficiency is a rare disorder with an estimated incidence in the western contries of one in 500,000. Because factor VII is important in initiation the coagulation cascade, a factor VII deficiency can result in significant bleeding with prolongation of the prothrombin time. We present a case of a factor VII deficiency with a subdural hematoma in an 18-year-old boy whose plasma activity of factor VII was < or =10%. Previously, he did not have any symptoms, such as hemarthrosis, easy bruising or bleeding after a minor trauma. He was administered fresh frozen plasma and a trephination was performed. His sister also had 51% lower level of factor VII.
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